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From148US$ /night
Check-in
12Dec2025Select date
Check-out
13Dec2025Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

601 Main Street, Buffalo, New York, United States, 14203
-
Close to Fountain Plaza
Perfect
7.8
8.4
/10
4.3
4.0
/5

Location

Located within Buffalo's Theatre District, Holiday Inn Express & Suites Buffalo Downtown is just a block away from the Buffalo Passport Agency and only minutes from Canalside. The hotel is also close to notable venues such as Shea's Performing Arts Center and Key Bank Center, both easily accessible via the Trolley Train. Guests can also explore attractions like Albright-Knox Art Gallery and Darwin Martin House within several blocks.

Medical Proximity

This hotel is situated near the Buffalo Niagara Medical Campus, a key district for healthcare professionals and families. Roswell Park Comprehensive Cancer Center, John R. Oishei Children's Hospital, and Buffalo General Hospital are all within a few blocks. This accessibility makes the hotel a convenient choice for medical travelers.

Unique Accommodation

All guest rooms are spacious suites featuring a separate bedroom with a king bed and a living area with a pullout couch. Each suite includes two 49-inch TVs, a microwave, a mini fridge, and a Keurig maker for added convenience. The hotel's layout encourages privacy, making it suitable for families and longer stays.

Dining Options

Adjacent to the hotel is TGI Friday's, offering lunch and dinner in a family-friendly atmosphere. Guests can start their day with the complimentary Express Start breakfast, featuring hot items such as eggs, pancakes, and cinnamon buns. The breakfast buffet ensures guests fuel up before exploring the sights of Buffalo.

Business and Fitness Facilities

The hotel includes a 24-hour business center with free printing services, catering to business travelers. A fitness center equipped with treadmills, free weights, and stretching bands is available for workouts. Additional services such as check-in and check-out enhancements are designed for guest convenience.

Highlights

Location: Downtown Buffalo's Theatre District

Medical: Near Buffalo Niagara Medical Campus

Rooms: Spacious suites with separate living areas

Dining: On-site TGI Friday's restaurant

Breakfast: Complimentary hot breakfast buffet

“This downtown property stands out for its practical location near the convention center and theater district. I appreciate the thoughtful extras geared toward business and medical travelers, including the on-site dining and proximity to passport services. The inclusion of free transport to nearby attractions adds considerable value for those looking to explore the area.”
Hotel logo
James DavidEditor-in-Chief at Cheaphotels
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Select your room type

The hotel provides a selection of rooms—doubles, family rooms, and suites—with perks like free cancellation, breakfast options, and great value deals
Queen Suite Roll Shower Disability Access
2 persons
42 m² 
1 King-size bed
Shower
Heating
One-Bedroom King Suite
2 persons
42 m² 
1 King-size bed and 1 Sofa bed
Heating
Bathtub
Standard Room
2 persons
42 m² 
1 Double bed
Heating
Bathtub
One-Bedroom Queen Room Mobility Accessible Tub Non-Smoking
2 persons
42 m² 
1 King-size bed
Heating
Bathtub
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Amenities & services

Real traveler stories and honest reviews—no glossy ads, just authentic feedback to guide your booking

General

  • No smoking on site
  • Free Wi-Fi
  • Parking
  • Safe deposit box
  • 24-hour reception
  • Express check-in/ -out
  • No pets allowed
  • Rooms/ Facilities for disabled
  • Security
  • Luggage storage
  • Lift
  • Vending machines
  • Smoke detectors
  • Fire extinguishers
  • Key card access
  • Key access

Sports & Fitness

  • Fitness centre

Services

  • Housekeeping
  • Laundry
  • Dry cleaning

Business

  • Business centre
  • Fax/Photocopying

Children

  • Board games

Spa & Leisure

  • Leisure/ TV room

Room features

  • Wi-Fi in rooms
  • Air conditioning
  • Heating
  • Sitting area
  • Tea and coffee facilities
  • Ironing facilities

Bathroom

  • Free toiletries

Media

  • Flat-screen TV
  • AM/FM alarm clock

Room decor

  • Carpeted floor
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Location

601 Main Street, Buffalo, New York, United States, 14203
Map view
601 Main Street, Buffalo, New York, United States, 14203
Nearby
Event hall
Buffalo Convention Center
270 m
Main and Chippewa Streets
Fountain Plaza
80 m
One M&T Plaza
One M&T Plaza
100 m
780 Main St at Edward St.
Saint Louis RC Church
570 m
Gallery
Western New York Book Arts Collaborative
390 m
Library
Buffalo and Erie County Public Library
280 m
West Chippewa Street
Chippewa Club Zone
240 m
617 Main St
Market Arcade Building
40 m
Gallery
CEPA Gallery
50 m
535 Washington St
The Electric Tower
200 m
Restaurants
EXPO Market
120 m
617 Main St Ste 200
Breezy Burrito Co
190 m
617 Main St
Prima Pizza Pasta
130 m
396 Pearl St Corner of Chippewa St
Mighty Taco
170 m
52 W Chippewa St
La Delicias Taqueria
250 m
454 Pearl St
Tim Hortons
270 m
424 Main St Rm 1102
Spot Coffee
310 m
225 Delaware Avenue
Tap House Pub & Grill
300 m
85 W Chippewa St
Jim's Steakout
310 m
92 W Chippewa St
Jake's Cafe
380 m
250 Delaware Ave
Explore Buffalo
Explore Buffalo
Top Attractions
Activities
Dining
Entertainment
Buffalo Convention Center
Buffalo Convention Center
4 minutes' walk
A hub for major events and conventions, featuring impressive architecture and various exhibits throughout the year.
Soldiers' and Sailors' Monument
Soldiers' and Sailors' Monument
8 minutes' walk
A tribute to veterans, showcasing detailed sculptures. The site offers historical insights and beautiful views.
Theodore Roosevelt Inaugural National Historic Site
Theodore Roosevelt Inaugural National Historic Site
19 minutes' walk
The birthplace of modern America features guided tours and interpretative displays, highlighting Roosevelt's impact.
Canalside
Canalside
20 minutes' walk
A waterfront destination with activities, events, and dining options. Perfect for families and enjoyment on warmer days.
Silo City Tours
15 minutes' walk
Guided tours of historic grain silos showcasing Buffalo's industrial past and art installations. Seasonal availability.
Buffalo Zoo
5 minutes' drive
An engaging experience for families featuring over 1,000 animals. Ideal for a day of relaxation amidst nature.
Biking along the Waterfront
20 minutes' walk
Bike rentals available near Canalside for a scenic ride along the waterfront, suitable for all skill levels.
EXPO Market
EXPO Market
2 minutes' walk
A vibrant food hall offering local specialties and casual dining options to satisfy diverse tastes from breakfast to dinner.
Breezy Burrito Co
Breezy Burrito Co
3 minutes' walk
Casual eatery known for its fresh burritos and tacos, perfect for a quick and satisfying meal. Vegetarian options available.
La Delicias Taqueria
La Delicias Taqueria
4 minutes' walk
Authentic Mexican cuisine in a cozy setting with hearty portions and flavorful dishes. Reservations recommended for busy nights.
KeyBank Center
KeyBank Center
25 minutes' walk
Home to concerts and sports events, offering a lively atmosphere. Check the calendar for family-friendly shows.
Buffalo Comedy Barn
6 minutes' drive
A fun venue featuring stand-up comedy and open-mic nights. A great spot for a relaxed evening filled with laughter.
Getting around town
City Centre
Buffalo3 min  ·  200 m
Airports
Buffalo Niagara International Airport (BUF)24 min  ·  15.9 km
Niagara Falls International Airport (IAG)49 min  ·  32.5 km
Train
Buffalo, NY Station16 min  ·  1.3 km
Bus
Bus stop3 min  ·  200 m
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Property information and rules
Check-in
from 15:00-23:59
Check-out
until 11 am
Guest Parking
Paid Public parking is possible at a location nearby.
Internet
is available in for free.
Breakfast
The hotel Holiday Inn Express & Suites Buffalo Downtown By Ihg serves a full breakfast for free. 
Children & extra beds
There are no cots provided in a room. 
Pets
Pets are not allowed.
Number of floors:
7
Number of rooms:
146
Former name
Comfort Suites
FAQs
About Holiday Inn Express & Suites Buffalo Downtown By Ihg
What are the check-in and check-out times at Holiday Inn Express & Suites Buffalo Downtown By Ihg?
Check-in is at 15:00 and check-out is at 11:00.
How far is Holiday Inn Express & Suites Buffalo Downtown By Ihg from Buffalo Niagara International Airport?
The hotel is located 20 km from Buffalo Niagara International Airport, approximately a 16-minute drive.
What amenities are available in the rooms at Holiday Inn Express & Suites Buffalo Downtown By Ihg?
Rooms include free Wi-Fi, air conditioning, a flat-screen TV, a microwave, a refrigerator, and a sofa bed.
What dining options are available near Holiday Inn Express & Suites Buffalo Downtown By Ihg?
Nearby restaurants include Bacchus Wine Bar & Restaurant, Breezy Burrito Co, and Dinosaur Bar-B-Que, all within 0.5 km.
What amenities does Holiday Inn Express & Suites Buffalo Downtown By Ihg offer for business travelers?
The hotel features a business center, complimentary Wi-Fi, and express check-in/check-out.
Does Holiday Inn Express & Suites Buffalo Downtown By Ihg have on-site parking?
The hotel does not have dedicated on-site parking, but public parking is available nearby.
What are the fitness options at Holiday Inn Express & Suites Buffalo Downtown By Ihg?
Guests have access to a 24-hour fitness center.
What breakfast options does Holiday Inn Express & Suites Buffalo Downtown By Ihg provide?
The hotel offers a complimentary hot breakfast buffet each morning.
What attractions are within walking distance of Holiday Inn Express & Suites Buffalo Downtown By Ihg?
Nearby attractions include Shea's Performing Arts Center, Buffalo Niagara Convention Center, and Key Bank Center.
Is there a shuttle service available at Holiday Inn Express & Suites Buffalo Downtown By Ihg?
The hotel offers a free shuttle service to local destinations, including casinos and events.
What entertainment options are near Holiday Inn Express & Suites Buffalo Downtown By Ihg?
Guests can enjoy local events and attractions, including concerts at the Town Ballroom and dining venues in the Chippewa Club Zone.

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